Description

tert-Butyl 3-((Hydroxyimino)Methyl)-1H-Indole-1-Carboxylate is a high-purity, protected indole derivative that serves as a critical synthetic intermediate in advanced organic synthesis. Its value lies in its dual functional groups, which allow for selective chemical transformations, making it indispensable for constructing complex molecular architectures. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides due to its indole-based scaffold.
• Organic Synthesis Reagent: Employed in academic and industrial labs for constructing complex heterocyclic compounds and natural product analogs.
• Peptide Mimetics: Serves as a precursor for non-natural amino acids and peptide-like structures in medicinal chemistry.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	tert-Butyl 3-((Hydroxyimino)Methyl)-1H-Indole-1-Carboxylate
CAS No.	188988-43-4
Molecular Formula	C15H18N2O3
Molecular Weight	274.32 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 3-[(hydroxyimino)methyl]-, 1,1-dimethylethyl ester; tert-Butyl 3-formylindole-1-carboxylate oxime; 1-Boc-3-(hydroxyiminomethyl)indole; Boc-3-CHO-indole oxime; 3-((Hydroxyimino)methyl)-1H-indole-1-carboxylic acid tert-butyl ester; 1-tert-Butoxycarbonyl-3-(hydroxyiminomethyl)indole; tert-Butyl 3-(hydroxyiminomethyl)-1H-indole-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-((Hydroxyimino)Methyl)-1H-Indole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided and available upon request, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.