Description

6-Chloro-5-(2-Piperazin-1-Yl-Ethyl)-1,3-Dihydro-Indol-2-One is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for research and development in medicinal chemistry, particularly for its role as a key building block in the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing central nervous system (CNS) and other targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific biological pathways and protein interactions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis projects and pharmacological research.

Basic Information

Product Name	6-Chloro-5-(2-Piperazin-1-Yl-Ethyl)-1,3-Dihydro-Indol-2-One
CAS No.	188797-79-7
Molecular Formula	C14H18ClN3O
Molecular Weight	279.77 g/mol
Synonyms	6-Chloro-5-[2-(piperazin-1-yl)ethyl]-1,3-dihydro-2H-indol-2-one; 6-Chloro-5-(2-piperazin-1-ylethyl)indolin-2-one; 2-Oxo-6-chloro-5-(2-piperazin-1-ylethyl)indoline; 188797-79-7; 6-Chloro-5-(2-piperazin-1-yl-ethyl)-1,3-dihydro-indol-2-one; 5-(2-Piperazin-1-ylethyl)-6-chloroindolin-2-one
EINECS	Contact for details

Quality Control

Our 6-Chloro-5-(2-Piperazin-1-Yl-Ethyl)-1,3-Dihydro-Indol-2-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.