Description

4,7-Methano-1H-Inden-1-Amine,2,3,3A,4,7,7A-Hexahydro-,[1S-(1Alpha,3Aalpha,4Alpha,7Alpha,7Aalpha)]-(9Ci) is a high-purity, stereochemically defined bicyclic amine building block. This compound is valued for its rigid, three-dimensional structure which is crucial for imparting specific conformational properties in advanced molecular synthesis. It serves as a critical intermediate for research and development in pharmaceutical chemistry, agrochemicals, and material science, where precise spatial orientation of functional groups is required. Our supply ensures consistent quality and reliable availability for global industrial and R&D applications.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its structural framework contributes to biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes to study enzyme function and biological pathways.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	4,7-Methano-1H-Inden-1-Amine,2,3,3A,4,7,7A-Hexahydro-,[1S-(1Alpha,3Aalpha,4Alpha,7Alpha,7Aalpha)]-(9Ci)
CAS No.	188000-52-4
Molecular Formula	C10H15N
Molecular Weight	149.23 g/mol
Synonyms	(1S,3aR,4S,7R,7aS)-2,3,3a,4,7,7a-Hexahydro-4,7-methano-1H-inden-1-amine; (1S,3aR,4S,7R,7aS)-Octahydro-4,7-methanoinden-1-amine; endo-2,3,3a,4,7,7a-Hexahydro-4,7-methano-1H-inden-1-amine; Bicyclo[2.2.1]heptane-2-methanamine, 1,3,3-trimethyl- (related structure); 1-Aminotrimethylenenorbornane; Chiral norbornane-based amine; [1S-(1α,3aα,4α,7α,7aα)]-2,3,3a,4,7,7a-Hexahydro-4,7-methano-1H-inden-1-amine
EINECS	Contact for details

Quality Control

Every batch of our 4,7-Methano-1H-Inden-1-Amine is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available for each lot. Our quality commitment supports compliance with cGMP and ISO guidelines where applicable for intermediate manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.