Description

2-Thiophenecarboxylicacid,4-Fluoro-5-Methyl-(9Ci) is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique thiophene core and fluorine substituent impart desirable biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate sophisticated sulfur-containing motifs into their molecular architectures.

Application

• As a critical synthetic intermediate in the research and development of new pharmaceutical candidates, particularly in medicinal chemistry programs.
• Utilized in the synthesis of advanced agrochemicals, such as herbicides and fungicides, where the thiophene scaffold enhances activity.
• Serves as a specialized building block for organic electronic materials, including semiconductors and conductive polymers.
• Used in academic and industrial R&D for method development and exploring novel fluorination chemistry on heterocyclic systems.
• Potential application as a ligand precursor in catalysis and coordination chemistry.
• Employed in the custom synthesis of complex molecules for contract research organizations (CROs) and CDMOs.

Basic Information

Product Name	2-Thiophenecarboxylicacid,4-Fluoro-5-Methyl-(9Ci)
CAS No.	187962-21-6
Molecular Formula	C7H5FO2S
Molecular Weight	172.18 g/mol
Synonyms	4-Fluoro-5-methyl-2-thiophenecarboxylic acid; 4-Fluoro-5-methylthiophene-2-carboxylic acid; 5-Methyl-4-fluorothiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-fluoro-5-methyl-; 4-Fluoro-5-methyl-2-thiophenecarboxylic acid (9CI); 187962-21-6; 4-Fluoro-5-methylthiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarboxylicacid,4-Fluoro-5-Methyl-(9Ci) is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.