Description

6-(3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Ylamino)-Hexanoic Acid is a specialized organic compound featuring a dihydroisoquinoline core linked to a hexanoic acid chain via an amino bridge. This unique structure makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents. The compound's defined molecular architecture supports the development of targeted molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Bioconjugation & Probe Development: Serves as a linker or functional handle for creating bioconjugates or fluorescent probes for biochemical assays.
• Chemical Biology: Employed in the development of chemical tools to study enzyme function and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes under cGMP conditions.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	6-(3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Ylamino)-Hexanoic Acid
CAS No.	187884-88-4
Molecular Formula	C17H24N2O2
Molecular Weight	288.39 g/mol
Synonyms	6-[(3,3-Dimethyl-3,4-dihydro-1H-isoquinolin-1-yl)amino]hexanoic acid; 6-[(3,3-Dimethyl-1,2,3,4-tetrahydroisoquinolin-1-yl)amino]hexanoic acid; 1-Amino-3,3-dimethyl-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid hexylamide derivative; UNII-9V6A6U6G4B; 187884-88-4; 6-(3,3-Dimethyl-3,4-dihydroisoquinolin-1-ylamino)hexanoic acid
EINECS	Contact for details

Quality Control

Our 6-(3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Ylamino)-Hexanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment. We support development needs with custom purity grades and specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under anhydrous conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.