Description

3-(3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Ylamino)-Propionic Acid is a specialized organic compound featuring a dihydroisoquinoline core linked to a propionic acid moiety via an amino bridge. This unique molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel bioactive molecules. The compound's structure is designed to impart specific pharmacological properties, making it critical for developing targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and cardiovascular pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Bioconjugation & Probe Development: Serves as a linker or functional handle for creating bioconjugates, fluorescent probes, or diagnostic agents.
• Chemical Biology: Employed in the development of enzyme inhibitors or receptor modulators for biological pathway analysis.
• Fine Chemical Synthesis: Used in multi-step organic syntheses to introduce the dihydroisoquinoline pharmacophore into complex molecules.
• Academic & Contract Research: Supplied to universities and CROs for exploratory research in organic and bioorganic chemistry.

Basic Information

Product Name	3-(3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Ylamino)-Propionic Acid
CAS No.	187884-87-3
Molecular Formula	C₁₄H₁₈N₂O₂
Molecular Weight	246.31 g/mol
Synonyms	1-Amino-3,3-dimethyl-3,4-dihydroisoquinoline-3-propanoic acid; 3-[(3,3-Dimethyl-3,4-dihydro-1-isoquinolinyl)amino]propanoic acid; 3,3-Dimethyl-1,2,3,4-tetrahydroisoquinoline-1-propanoic acid; 187884-87-3; 3-(3,3-Dimethyl-1,2,3,4-tetrahydroisoquinolin-1-ylamino)propionic acid; 3-(3,3-Dimethyl-3,4-dihydro-1(2H)-isoquinolinylamino)propanoic acid
EINECS	Contact for details

Quality Control

Our 3-(3,3-Dimethyl-3,4-Dihydro-Isoquinolin-1-Ylamino)-Propionic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.