Description

Derquantel is a potent anthelmintic compound belonging to the spiroindole class, specifically developed for veterinary and potential pharmaceutical applications. Its primary value lies in its unique mode of action, targeting parasite-specific nicotinic acetylcholine receptors, which makes it a critical tool in combating parasitic resistance. This high-purity active pharmaceutical ingredient (API) is essential for manufacturers in the veterinary pharmaceutical industry developing next-generation parasiticides, as well as for research institutions studying novel anthelmintic therapies.

Application

• Veterinary Anthelmintic Formulations: As a key active ingredient in combination therapies (e.g., with abamectin) for the control of gastrointestinal nematodes in livestock such as sheep and cattle.
• Parasiticide R&D: Serves as a reference standard and building block in pharmaceutical research for developing new antiparasitic drugs.
• Animal Health Products: Used in the development of injectable, oral, or topical solutions and suspensions for veterinary use.
• Mode of Action Studies: Employed in biochemical and pharmacological research to study novel pathways for parasite neuromuscular inhibition.
• Resistance Management Programs: Integral to strategic deworming programs aimed at mitigating the rise of multi-drug resistant parasite strains.

Basic Information

Product Name	Derquantel
CAS No.	187865-22-1
Molecular Formula	C₂₅H₂₈F₃N₃O₂
Molecular Weight	459.51 g/mol
Synonyms	2-Desoxoparaherquamide; PNU-141962; (1R,3S,4S,5'S,6'S)-6'-[(1S)-1-(4-Fluorophenyl)ethyl]-5'-methyl-3-propylspiro[1H-indole-3,4'-piperidine]-2,2'(3'H)-dione; 2-Deoxyparaherquamide; Derquantelum; Startect (combination product name); Spiroindole anthelmintic
EINECS	Contact for details

Quality Control

Our Derquantel CAS NO 187865-22-1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical R&D and formulation. Specifications typically align with pharmaceutical-grade requirements, with identity, purity, and impurity profiles verified by advanced chromatographic and spectroscopic methods. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.