Description

Benzamide, 4-Mercapto-n-Methyl- CAS NO 187160-34-5 is a specialized organic compound featuring a benzamide core substituted with a methyl group and a reactive mercapto (thiol) moiety. This unique structure makes it a valuable building block and intermediate in advanced chemical synthesis, particularly where the introduction of a sulfur-containing functional group is required. It is primarily utilized by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, especially those targeting neurological disorders or possessing specific receptor-binding activities.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, or insecticides where the thiol group can be leveraged for bioactivity or as a synthetic handle.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, ligands for metal-organic frameworks (MOFs), or surface-modifying agents.
• Chemical Biology & Proteomics: Acts as a reactive probe or linker due to the thiol group's affinity for metal ions or its ability to form disulfide bonds, useful in studying protein interactions.
• Catalyst Ligand Development: Employed in the design of novel chiral or achiral ligands for transition metal catalysis in asymmetric synthesis.
• Fine Chemical Production: An intermediate for manufacturing dyes, pigments, or other complex organic molecules requiring a benzamide-thiol architecture.

Basic Information

Product Name	Benzamide, 4-Mercapto-n-Methyl-
CAS No.	187160-34-5
Molecular Formula	C8H9NOS
Molecular Weight	167.23 g/mol
Synonyms	4-Mercapto-N-methylbenzamide; N-Methyl-4-mercaptobenzamide; 4-(Methylcarbamoyl)benzenethiol; p-Mercapto-N-methylbenzamide; 4-Sulfanyl-N-methylbenzamide; 4-Thiol-N-methylbenzamide; Benzamide, N-methyl-4-mercapto-; 187160-34-5 (CAS)
EINECS	Contact for details

Quality Control

Our production of Benzamide, 4-Mercapto-n-Methyl- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and industrial use. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP and ISO 9001 compliant manufacturing practices upon request for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its easily oxidized nature, minimize exposure to air and oxidizing agents. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.