Description

2-Amino-n-Benzyl-3-(1H-Indol-3-Yl)-Propionamide is a specialized indole derivative with a benzyl-protected amide structure, serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of pharmacologically active molecules, particularly those targeting neurological and oncological pathways. It is primarily needed by research institutions and pharmaceutical companies engaged in drug discovery and process chemistry for creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those with indole-based scaffolds.
• Peptidomimetic Research: Used in the design and construction of peptide analogs and enzyme inhibitors due to its amino acid-like structure.
• Medicinal Chemistry: Serves as a versatile building block for structure-activity relationship (SAR) studies and lead optimization programs.
• Bioconjugation: Potential use in linker chemistry for antibody-drug conjugates (ADCs) or other targeted delivery systems.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein functions.
• Academic & Contract Research: Utilized in university and CRO settings for exploratory synthetic chemistry and methodological development.

Basic Information

Product Name	2-Amino-n-Benzyl-3-(1H-Indol-3-Yl)-Propionamide
CAS No.	187085-81-0
Molecular Formula	C19H21N3O
Molecular Weight	307.39 g/mol
Synonyms	2-Amino-N-benzyl-3-(1H-indol-3-yl)propanamide; 3-(1H-Indol-3-yl)-2-amino-N-benzylpropionamide; N-Benzyl-2-amino-3-(3-indolyl)propionamide; 2-Amino-3-(1H-indol-3-yl)-N-(phenylmethyl)propanamide; (2S)-2-Amino-N-benzyl-3-(1H-indol-3-yl)propanamide (for stereoisomer); Tryptophan benzylamide derivative; α-Amino-N-benzyl-β-(3-indolyl)propionamide
EINECS	Contact for details

Quality Control

Our 2-Amino-n-Benzyl-3-(1H-Indol-3-Yl)-Propionamide is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.