Description

5-Amino-1-tert-Butyl-3-(4-Methylphenyl)-4-Cyanopyrazole is a high-value, multi-functional pyrazole derivative with a complex heterocyclic structure. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in organic synthesis. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used as a core scaffold for developing new generation pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in organometallic chemistry to create specialized ligands for catalytic processes and material science applications.
• Dye and Pigment Intermediate: Functions as a building block for synthesizing advanced colorants and functional dyes with specific light-absorbing properties.
• Polymer Additive: Can be incorporated into polymer chains to modify thermal stability, UV resistance, or other material properties.
• Research & Development: Essential for academic and industrial research exploring new heterocyclic chemistry, structure-activity relationships (SAR), and bioisosteric replacements.

Basic Information

Product Name	5-Amino-1-tert-Butyl-3-(4-Methylphenyl)-4-Cyanopyrazole
CAS No.	186896-24-2
Molecular Formula	C15H18N4
Molecular Weight	254.33 g/mol
Synonyms	5-Amino-1-(tert-butyl)-3-(p-tolyl)-1H-pyrazole-4-carbonitrile; 1-tert-Butyl-5-amino-3-(4-methylphenyl)pyrazole-4-carbonitrile; 4-Cyano-5-amino-1-tert-butyl-3-(4-methylphenyl)pyrazole; 5-Amino-1-tert-butyl-3-(4-methylphenyl)-1H-pyrazole-4-carbonitrile; 5-Amino-1-(1,1-dimethylethyl)-3-(4-methylphenyl)-1H-pyrazole-4-carbonitrile
EINECS	Contact for details

Quality Control

Our production of 5-Amino-1-tert-Butyl-3-(4-Methylphenyl)-4-Cyanopyrazole adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the rigorous standards required for GMP-grade intermediates and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.