Description

5-Formyl-2-[(2-Nitrophenyl)Amino]-3-Cyanothiophene is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. Its molecular architecture, featuring formyl, cyano, and nitroanilino substituents on a thiophene core, makes it a versatile precursor for constructing complex molecular frameworks. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for molecules with thiophene-based pharmacophores.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Organic Electronic Materials: Acts as a precursor in the synthesis of conjugated polymers and small molecules for applications in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Dye and Pigment Chemistry: Employed in the development of advanced colorants and functional dyes due to its electron-accepting nitro and cyano groups.
• Coordination Chemistry & Ligand Design: The formyl and amino groups provide chelation sites for metal ions, useful in creating catalysts or metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for methodological studies in heterocyclic and cross-coupling chemistry within university and corporate research laboratories.

Basic Information

Product Name	5-Formyl-2-[(2-Nitrophenyl)Amino]-3-Cyanothiophene
CAS No.	186792-87-0
Molecular Formula	C12H7N3O3S
Molecular Weight	273.27 g/mol
Synonyms	2-[(2-Nitrophenyl)amino]-3-cyano-5-formylthiophene; 3-Cyano-5-formyl-2-[(2-nitrophenyl)amino]thiophene; 5-Formyl-2-[(2-nitrophenyl)amino]thiophene-3-carbonitrile; 2-Amino-3-cyano-5-formylthiophene, N-(2-nitrophenyl)-; Thiophene-3-carbonitrile, 2-[(2-nitrophenyl)amino]-5-formyl-
EINECS	Contact for details

Quality Control

Every batch of 5-Formyl-2-[(2-Nitrophenyl)Amino]-3-Cyanothiophene is manufactured under strict quality management protocols and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality systems support compliance with cGMP standards for pharmaceutical intermediates, and we welcome client audits and specification reviews.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.