Description

tert-Butyl 3-Methyl-1H-Pyrazole-1-Carboxylate is a protected pyrazole derivative that serves as a versatile and critical building block in advanced organic synthesis. Its primary value lies in providing a stable, reactive intermediate for constructing complex heterocyclic scaffolds, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazole or related heterocyclic cores.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that leverage the pyrazole moiety for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the development of advanced organic materials, including polymers and liquid crystals with specific electronic or optical properties.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and tools to study biological systems and enzyme functions.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	tert-Butyl 3-Methyl-1H-Pyrazole-1-Carboxylate
CAS No.	186551-70-2
Molecular Formula	C9H14N2O2
Molecular Weight	182.22 g/mol
Synonyms	1-Boc-3-methylpyrazole; 3-Methyl-1H-pyrazole-1-carboxylic acid tert-butyl ester; tert-Butyl 3-methylpyrazole-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-methyl-1H-pyrazole; Boc-3-methylpyrazole; 3-Methyl-1-(tert-butoxycarbonyl)pyrazole; Pyrazole-1-carboxylic acid, 3-methyl-, 1,1-dimethylethyl ester; 1H-Pyrazole-1-carboxylic acid, 3-methyl-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Methyl-1H-Pyrazole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliable supply for research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Melting Point	Contact for details
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.