Description

Ethyl 5-Bromo-4-Methyl-2-Thiophenecarboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound is valued for its reactive bromine and ester functional groups, enabling precise molecular construction in complex chemical pathways. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules containing functionalized thiophene cores.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides where the thiophene moiety contributes to biological activity.
• Material Science Research: Serves as a precursor for the synthesis of organic semiconductors, conductive polymers, and non-linear optical (NLO) materials.
• Ligand and Catalyst Development: Employed in creating specialized ligands for metal catalysis and organocatalysts due to its modifiable structure.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: An important starting material for custom synthesis houses and CDMOs serving the global fine chemical market.

Basic Information

Product Name	Ethyl 5-Bromo-4-Methyl-2-Thiophenecarboxylate
CAS No.	186521-81-3
Molecular Formula	C8H9BrO2S
Molecular Weight	249.13 g/mol
Synonyms	5-Bromo-4-methyl-2-thiophenecarboxylic acid ethyl ester; Ethyl 5-bromo-4-methylthiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 5-bromo-4-methyl-, ethyl ester; 186521-81-3; 5-Bromo-4-methylthiophene-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Bromo-4-Methyl-2-Thiophenecarboxylate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications for identity, purity, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming batch-specific results from techniques including HPLC, GC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.