Description

4-Bromo-1H-Indazole is a versatile and high-value brominated heterocyclic building block essential for modern synthetic chemistry. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of kinase inhibitors, anticancer agents, and other biologically active molecules targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its heterocyclic core for bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs and other optoelectronic devices.
• Chemical Biology: Employed as a molecular probe or a tagging reagent in proteomics and medicinal chemistry research.
• Organic Synthesis: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce the indazole moiety.
• Dye & Pigment Industry: Acts as an intermediate for synthesizing specialized dyes and pigments with unique coloristic properties.

Basic Information

Product Name	4-Bromo-1H-Indazole
CAS No.	186407-74-9
Molecular Formula	C7H5BrN2
Molecular Weight	197.03 g/mol
Synonyms	4-Bromo-1H-indazole; 4-Bromoindazole; 1H-Indazole, 4-bromo-; 4-Br-1H-Indazole; NSC 405124; 186407-74-9; 4-Bromo-1H-benzo[d]imidazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.