Description

tert-Butyl6-Nitro-3,4-Dihydroisoquinoline-2(1H)-Carboxylate is a high-purity, protected heterocyclic building block of significant value in advanced organic synthesis. This compound is specifically designed to serve as a key intermediate in the development of complex pharmaceutical molecules, offering a strategic point for further functionalization. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and cardiovascular diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold for biological activity.
• Organic Synthesis Building Block: Employed in academic and industrial research for constructing complex nitrogen-containing heterocycles due to its reactive nitro and protected amine functionalities.
• Material Science Precursor: Can be utilized in the synthesis of organic ligands for catalysts or novel organic electronic materials.

Basic Information

Product Name	tert-Butyl6-Nitro-3,4-Dihydroisoquinoline-2(1H)-Carboxylate
CAS No.	186390-79-4
Molecular Formula	C₁₄H₁₈N₂O₄
Molecular Weight	278.31 g/mol
Synonyms	tert-Butyl 6-nitro-1,2,3,4-tetrahydroisoquinoline-2-carboxylate; 2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-6-nitro-, 1,1-dimethylethyl ester; 6-Nitro-1,2,3,4-tetrahydroisoquinoline-2-carboxylic acid tert-butyl ester; Boc-6-Nitro-Tic-OH; 186390-79-4; tert-Butyl 6-nitro-3,4-dihydro-2H-isoquinoline-1-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl6-Nitro-3,4-Dihydroisoquinoline-2(1H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming the product meets the agreed specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.