Description

6,6-Dimethyl-3-(Methylsulfinyl)-4-Oxo-4,5,6,7-Tetrahydrobenzo[C]Thiophene-1-Carbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule drugs, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of novel drug candidates, especially in medicinal chemistry programs.
• Oncology Research: Used in the development of targeted cancer therapies due to its potential as a core scaffold for kinase inhibitors or other targeted agents.
• CNS Drug Discovery: Applied in the research and synthesis of compounds for neurological and psychiatric disorders.
• Chemical Biology: Acts as a probe or precursor in studying enzyme function and biological pathways.
• Process Chemistry Development: Employed in scaling up and optimizing synthetic routes for potential commercial API production.
• Custom Synthesis: Provided as a starting material for contract research organizations (CROs) and CDMOs for client-specific projects.

Basic Information

Product Name	6,6-Dimethyl-3-(Methylsulfinyl)-4-Oxo-4,5,6,7-Tetrahydrobenzo[C]Thiophene-1-Carbonitrile
CAS No.	186371-17-5
Molecular Formula	C₁₂H₁₃NO₂S₂
Molecular Weight	267.37 g/mol
Synonyms	6,6-Dimethyl-3-(methylsulfinyl)-4-oxo-4,5,6,7-tetrahydro-1-benzothiophene-1-carbonitrile; 4,5,6,7-Tetrahydro-6,6-dimethyl-3-(methylsulfinyl)-4-oxobenzo[c]thiophene-1-carbonitrile; Benzo[c]thiophene-1-carbonitrile, 4,5,6,7-tetrahydro-6,6-dimethyl-3-(methylsulfinyl)-4-oxo-; CAS 186371-17-5
EINECS	Contact for details

Quality Control

Our 6,6-Dimethyl-3-(Methylsulfinyl)-4-Oxo-4,5,6,7-Tetrahydrobenzo[C]Thiophene-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.