Description

(R)-2-Chloro-1-(4-Methoxyphenyl)Ethanol is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its role as a key building block in the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing active pharmaceutical ingredients (APIs) and other specialty products.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of enantiomerically pure Active Pharmaceutical Ingredients (APIs), particularly in cardiovascular and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides, where specific stereochemistry is required for biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for stereoselective chemical transformations.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances that require high enantiomeric purity.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry, particularly in studies involving stereocontrolled chlorohydrin formation and subsequent functionalization.

Basic Information

Product Name	(R)-2-Chloro-1-(4-Methoxyphenyl)Ethanol
CAS No.	186345-05-1
Molecular Formula	C9H11ClO2
Molecular Weight	186.64 g/mol
Synonyms	(R)-2-Chloro-1-(4-methoxyphenyl)ethanol; (R)-1-(4-Methoxyphenyl)-2-chloroethanol; (R)-p-Methoxy-α-chlorobenzyl alcohol; (R)-2-Chloro-1-(4-methoxyphenyl)ethan-1-ol; (R)-4-Methoxy-α-chlorobenzyl alcohol; (R)-O-Methyltyrosinol chlorohydrin; (R)-Chlorohydrin of 4-methoxybenzaldehyde
EINECS	Contact for details

Quality Control

Our (R)-2-Chloro-1-(4-Methoxyphenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) determination, to ensure it meets the high-purity standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.