Description

1H-Indole-2-Carboxylicacid,Octahydro-,(2S)-(9Ci) is a chiral, saturated indole derivative that serves as a sophisticated building block in advanced organic synthesis. Its unique stereochemistry and rigid, bicyclic framework make it a valuable intermediate for constructing complex molecules with precise three-dimensional architecture. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry, asymmetric synthesis, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Asymmetric Catalysis Ligand Precursor: Used in the synthesis of novel chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Research: Serves as a core structure for developing new pesticides and herbicides with enhanced specificity and lower environmental impact.
• Peptidomimetics & Bioactive Molecule Design: Its constrained, polycyclic structure is ideal for mimicking peptide turns and designing protease inhibitors or receptor modulators.
• Academic & Industrial R&D: Employed in methodological studies and the discovery of new chemical entities across various life science disciplines.
• Fine Chemical Synthesis: Used in the custom synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical purity.

Basic Information

Product Name	1H-Indole-2-Carboxylicacid,Octahydro-,(2S)-(9Ci)
CAS No.	186194-75-2
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2S)-Octahydro-1H-indole-2-carboxylic acid; (2S)-Octahydroindole-2-carboxylic acid; (S)-Octahydroindole-2-carboxylic acid; (S)-2-Carboxyhexahydropyrrolo[1,2-a]pyrazine; (S)-Perhydroindole-2-carboxylic acid; (S)-2-Carboxy-1,2,3,4,5,6,7,8-octahydroindole; (2S)-2,3,3a,4,5,6,7,7a-Octahydro-1H-indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 1H-Indole-2-Carboxylicacid,Octahydro-,(2S)-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical characterization, including chiral purity verification, to meet the exacting standards of research and process chemistry. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile data is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be handled in a compatible environment, as it is soluble in strong acid/organic solvent systems. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.