Description

Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, Methyl Ester, (1S-Exo)- (9Ci) is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound matters because its rigid, functionalized norbornane skeleton serves as a key intermediate in the development of complex pharmaceuticals, agrochemicals, and specialty materials. It is particularly needed by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing molecules with specific three-dimensional architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring the norbornane framework for biological activity or metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the bicyclic structure imparts desired physical and biological properties.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the development of novel polymers, resins, and specialty chemicals with unique thermal or mechanical properties derived from its rigid core.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex, naturally-inspired odorants and flavor compounds.
• Academic and R&D Laboratories: A valuable tool for methodological studies in organic chemistry, including cycloaddition reactions and stereochemical investigations.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, Methyl Ester, (1S-Exo)- (9Ci)
CAS No.	186182-40-1
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1S,2R,4S)-Bicyclo[2.2.1]heptane-2-carboxylic acid methyl ester; (1S-endo)-(-)-Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, methyl ester (precursor); exo-(-)-Methyl 2-norbornanecarboxylate; (1S,2R,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-yl methyl ester (related); L-(-)-Bornyl acetate derivative; endo-Bicyclo[2.2.1]hept-5-ene-2-methyl carboxylate; Methyl (1S,2R,4S)-bicyclo[2.2.1]heptane-2-carboxylate
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Heptane-2-Carboxylic Acid, Methyl Ester, (1S-Exo)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with full analytical data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.