Description

N,n-Dimethyl-D6-Formamide is a deuterated isotopologue of the common polar aprotic solvent N,N-Dimethylformamide (DMF). This compound is specifically engineered for applications requiring precise spectroscopic analysis and mechanistic studies, where the replacement of hydrogen with deuterium is critical. It is an essential reagent for NMR spectroscopy, organic synthesis research, and the development of labeled pharmaceutical compounds.

Application

• NMR Spectroscopy Solvent: Primary application as a deuterated solvent for proton NMR, providing a non-interfering signal background for accurate structural analysis of organic molecules.
• Mechanistic Reaction Studies: Used as a labeled reagent in kinetic isotope effect (KIE) studies to elucidate reaction pathways and mechanisms in organic and organometallic chemistry.
• Pharmaceutical Research & Development: Serves as a precursor or intermediate in the synthesis of deuterated active pharmaceutical ingredients (APIs) for improved metabolic stability and pharmacokinetic profiling.
• Advanced Material Synthesis: Employed in the synthesis of deuterated polymers and specialty materials where isotopic labeling is required for analytical tracking or to modify physical properties.
• Analytical Chemistry Standard: Utilized as an internal standard or reference material in mass spectrometry (MS) and other analytical techniques requiring high isotopic purity.

Basic Information

Product Name	N,n-Dimethyl-D6-Formamide
CAS No.	185990-36-7
Molecular Formula	C3D7NO
Molecular Weight	79.13 g/mol
Synonyms	Deuterated DMF; DMF-d7; Perdeuterated N,N-Dimethylformamide; N,N-Dimethylformamide-d7; (Dimethylamino-d6)formaldehyde; Hexadeutero-dimethylformamide; DMF Deuterated Solvent; Formdimethylamide-d7
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-D6-Formamide is produced under stringent conditions to ensure high isotopic and chemical purity, meeting the exacting requirements of research and analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as isotopic enrichment (D-atom %), chemical purity, and spectroscopic suitability. We adhere to rigorous internal quality standards to guarantee batch-to-batch consistency and reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect isotopic purity and analytical performance.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Isotopic Purity (D-atom %)	≥ 99.5%
Chemical Purity (GC)	≥ 99.9%
Water Content (KF)	≤ 0.05%
NMR Solvent Suitability	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.