Description

Satavaptan is a selective, non-peptide vasopressin V2 receptor antagonist. This compound is of significant interest in pharmaceutical research and development for its potential therapeutic applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of treatments for conditions related to fluid balance, such as hyponatremia. Satavaptan CAS NO 185913-78-4 represents a high-purity chemical entity for advanced investigative and formulation work.

Application

• Pharmaceutical Reference Standard: Serves as a primary standard for analytical method development and validation in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Used in the research-scale synthesis and process development of novel drug candidates targeting vasopressin pathways.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate the physiology of vasopressin receptors and their role in water-electrolyte homeostasis.
• Preclinical Development: A key material for pharmacokinetic, pharmacodynamic, and toxicology studies during the drug discovery pipeline.
• Formulation Research: Used in the development of various dosage forms to study stability, compatibility, and delivery mechanisms.

Basic Information

Product Name	Satavaptan
CAS No.	185913-78-4
Molecular Formula	C26H25FN4O4
Molecular Weight	476.50 g/mol
Synonyms	SR 121463; SR-121463; SR121463; 5-Fluoro-2-methyl-N-[4-(5H-pyrrolo[2,1-c][1,4]benzodiazepin-10(11H)-ylcarbonyl)-3-chlorophenyl]benzamide; (R)-N-(4-(5,11-Dihydro-10H-dibenzo[b,e][1,4]diazepin-11-yl)-1-piperazinyl)-2-fluorobenzamide (isomer related); Satavaptanum; UNII-8V71L1X1S5
EINECS	Contact for details

Quality Control

Our Satavaptan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with the agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.