Description

(3Ar,4R,6As)-3A,6A-Dihydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxol-4-Ol is a high-purity chiral building block and synthetic intermediate of significant value in advanced organic synthesis. Its defined stereochemistry makes it a critical precursor for the production of complex, biologically active molecules, ensuring precise control over the final product's structure and activity. This compound is essential for research and development in the pharmaceutical and fine chemical industries, particularly for chemists developing new active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially in antiviral, anticancer, and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where specific stereochemistry is required for optimal biological activity.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Fine Chemical Production: Employed in the manufacture of complex fragrance and flavor ingredients that require high stereochemical purity.
• Academic & Industrial R&D: A valuable tool for synthetic organic chemists in universities and corporate labs exploring new synthetic methodologies and compound libraries.
• Material Science: Potential monomer or intermediate for creating specialized polymers with unique optical or structural properties.

Basic Information

Item	Details
Product Name	(3Ar,4R,6As)-3A,6A-Dihydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxol-4-Ol
CAS No.	185622-62-2
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	(3aR,4R,6aS)-3a,6a-Dihydro-2,2-dimethyl-4H-cyclopenta[d][1,3]dioxol-4-ol; (3aR,4R,6aS)-2,2-Dimethyl-3a,4,6,6a-tetrahydro-4H-cyclopenta[d][1,3]dioxol-4-ol; (4R)-2,2-Dimethyl-4-hydroxy-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxole; Chiral Cyclopentanedioxolol; (R)-Glyceraldehyde Acetonide Cyclopentene Adduct
EINECS	Contact for details

Quality Control

Every batch of (3Ar,4R,6As)-3A,6A-Dihydro-2,2-Dimethyl-4H-Cyclopenta-1,3-Dioxol-4-Ol is manufactured and tested under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to ensure high enantiomeric excess (ee) and chemical purity, meeting the stringent requirements of pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.