Description

(4-Bromo-2-Chlorophenyl)Methanol CAS NO 185315-48-4 is a versatile halogenated benzyl alcohol derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive bromine atom and a hydroxymethyl group, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by pharmaceutical and agrochemical research and development teams for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Materials: Serves as a building block for creating advanced functional materials used in electronic displays and optoelectronic devices.
• Polymer & Resin Modifier: Incorporated into specialty polymers to alter physical properties such as thermal stability and flame retardancy.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed Suzuki, Heck, and Buchwald-Hartwig amination reactions.
• Fine Chemical & Dye Intermediate: Utilized in the multi-step synthesis of complex dyes, pigments, and other high-value fine chemicals.

Basic Information

Product Name	(4-Bromo-2-Chlorophenyl)Methanol
CAS No.	185315-48-4
Molecular Formula	C7H6BrClO
Molecular Weight	221.48 g/mol
Synonyms	4-Bromo-2-chlorobenzyl alcohol; (4-Bromo-2-chlorophenyl)methanol; 2-Chloro-4-bromobenzyl alcohol; 1-(Bromomethyl)-2-chloro-4-bromobenzene (deprecated); α-Hydroxymethyl-4-bromo-2-chlorobenzene; Benzenemethanol, 4-bromo-2-chloro-; (4-Br-2-Cl-C6H3)CH2OH
EINECS	Contact for details

Quality Control

Our (4-Bromo-2-Chlorophenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up processes. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.