Description

3-[3-(2-Dimethylaminoethyl)-1H-Indol-5-Yl]-n-(4-Methoxybenzyl)Acrylamide is a specialized, high-purity synthetic intermediate of significant interest in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel pharmacologically active molecules, particularly within medicinal chemistry research. It is primarily needed by R&D laboratories and pharmaceutical companies focused on creating new therapeutic agents, especially those targeting neurological pathways and receptor modulation.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Employed in academic and industrial research to study specific biological pathways and receptor interactions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Reference Standard: Utilized as an analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-[3-(2-Dimethylaminoethyl)-1H-Indol-5-Yl]-n-(4-Methoxybenzyl)Acrylamide
CAS No.	185259-85-2
Molecular Formula	C23H27N3O2
Molecular Weight	377.48 g/mol
Synonyms	N-[(4-Methoxyphenyl)methyl]-3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]prop-2-enamide; 3-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-(4-methoxybenzyl)acrylamide; Acrylamide, 3-[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]-N-[(4-methoxyphenyl)methyl]-; Tryptamine-based acrylamide derivative
EINECS	Contact for details

Quality Control

Our 3-[3-(2-Dimethylaminoethyl)-1H-Indol-5-Yl]-n-(4-Methoxybenzyl)Acrylamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.