Description

1H-Indole, 4-Fluoro-3-(1,2,3,6-Tetrahydro-4-Pyridinyl)- is a high-purity, advanced pharmaceutical intermediate featuring a complex indole-piperidine hybrid structure. This compound is of significant value for its role as a key building block in the synthesis of novel bioactive molecules, particularly within central nervous system (CNS) drug discovery. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, where precise chemical architecture is critical for biological activity.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting neurological receptors.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity in new chemical entities.
• CNS Drug Discovery: Serves as a core structural component in the research and development of compounds for neurological and psychiatric disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Reference Standard: Can be utilized as an analytical standard for quality control and method development in API manufacturing.
• Biochemical Tool Compound: Employed in vitro and in vivo studies to investigate specific biological pathways and mechanisms of action.

Basic Information

Product Name	1H-Indole, 4-Fluoro-3-(1,2,3,6-Tetrahydro-4-Pyridinyl)-
CAS No.	185255-80-5
Molecular Formula	C13H13FN2
Molecular Weight	216.26 g/mol
Synonyms	4-Fluoro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole; 3-(1,2,3,6-Tetrahydro-4-pyridinyl)-4-fluoro-1H-indole; 4-Fluoro-3-(1,2,3,6-tetrahydro-4-pyridinyl)indole; 4-Fluoro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indole; 4-Fluoro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole; 185255-80-5
EINECS	Contact for details

Quality Control

Our 1H-Indole, 4-Fluoro-3-(1,2,3,6-Tetrahydro-4-Pyridinyl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.