Description

Methyl 1,2,3,4-Tetrahydroisoquinoline-6-Carboxylate is a versatile heterocyclic building block and key synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its tetrahydroisoquinoline core, a privileged scaffold found in numerous biologically active molecules and pharmaceuticals. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients and complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of drug candidates, particularly those targeting neurological disorders, cardiovascular diseases, and cancer.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and insecticides with specific modes of action.
• Fine Chemical Synthesis: Serves as a key starting material for synthesizing complex dyes, pigments, and specialty chemicals.
• Academic & R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.
• Ligand and Catalyst Development: Utilized in the preparation of novel chiral ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	Methyl 1,2,3,4-Tetrahydroisoquinoline-6-Carboxylate
CAS No.	185057-00-5
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	6-(Methoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline; Methyl 6-isoquinolinecarboxylate, 1,2,3,4-tetrahydro-; 1,2,3,4-Tetrahydroisoquinoline-6-carboxylic acid methyl ester; 6-Carbomethoxy-1,2,3,4-tetrahydroisoquinoline; Methyl tetrahydroisoquinoline-6-carboxylate; THIQ-6-COOMe; 6-Methoxycarbonyl-THIQ
EINECS	Contact for details

Quality Control

Our Methyl 1,2,3,4-Tetrahydroisoquinoline-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque or amber packaging.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.