Description

4-Pyridinemethanol,α-2-Propynyl-(9Ci) is a specialized pyridine derivative with a propargyl alcohol functional group, offering a unique combination of a heterocyclic aromatic system and a reactive alkyne moiety. This compound is valued as a versatile chemical building block and intermediate for advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists working on novel active ingredients, fine chemicals, and material science applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of advanced polymers, coatings, or functionalized surfaces where the pyridine and alkyne groups impart specific properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes, leveraging its click chemistry compatibility via the alkyne group.
• Fine Chemical Production: Functions as a high-value intermediate in custom synthesis and contract manufacturing for specialty chemicals.

Basic Information

Product Name	4-Pyridinemethanol,α-2-Propynyl-(9Ci)
CAS No.	184827-11-0
Molecular Formula	C9H9NO
Molecular Weight	147.17 g/mol
Synonyms	α-(2-Propynyl)-4-pyridinemethanol; 4-(2-Propynyloxymethyl)pyridine; 2-Propynyl 4-pyridylmethyl ether; (4-Pyridyl)methyl propargyl ether; Propargyl 4-pyridylmethyl ether; 4-((Prop-2-yn-1-yloxy)methyl)pyridine; 4-Pyridylmethyl propargyl ether; 184827-11-0
EINECS	Contact for details

Quality Control

Our 4-Pyridinemethanol,α-2-Propynyl-(9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results for parameters including assay, related substances, and residual solvents. Our quality systems support development and cGMP manufacturing requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.