Description

(S)-4-Phenyl-3-Propionyl-2-Oxazolidinone is a high-purity chiral auxiliary and synthetic building block of significant importance in asymmetric organic synthesis. Its value lies in its ability to induce high stereoselectivity in key reactions, enabling the production of enantiomerically pure intermediates for complex molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral reagents.

Application

• Asymmetric Synthesis: As a versatile chiral auxiliary for Evans aldol reactions and other stereocontrolled transformations.
• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• Agrochemical Development: Used in the research and production of enantiomerically pure herbicides, fungicides, and insecticides.
• Catalyst and Ligand Preparation: Serves as a precursor for chiral catalysts and ligands used in homogeneous catalysis.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and process optimization.
• Fine Chemical Manufacturing: Employed in the custom synthesis of specialty chemicals and advanced materials.

Basic Information

Product Name	(S)-4-Phenyl-3-Propionyl-2-Oxazolidinone
CAS No.	184363-66-4
Molecular Formula	C12H13NO3
Molecular Weight	219.24 g/mol
Synonyms	(4S)-4-Phenyl-3-propionyl-2-oxazolidinone; (S)-4-Phenyl-3-propionyloxazolidin-2-one; (S)-3-Propionyl-4-phenyloxazolidin-2-one; Evans Auxiliary (Propionyl); (S)-N-Propionyl-4-phenyl-2-oxazolidinone; (S)-(-)-4-Phenyl-3-propionyl-2-oxazolidinone
EINECS	Contact for details

Quality Control

Our (S)-4-Phenyl-3-Propionyl-2-Oxazolidinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for sensitive asymmetric synthesis. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Melting Point	78 - 82 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.