Description

5-(Chloromethyl)-1-Methyl-3-(Trifluoromethyl)-1H-Pyrazole is a versatile and high-value pyrazole-based building block, essential for advanced synthetic chemistry. Its core value lies in the strategic combination of a reactive chloromethyl group and a stable trifluoromethyl moiety, enabling precise molecular modifications. This compound is primarily sought after by R&D chemists and process developers in the pharmaceutical and agrochemical industries for constructing novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized pyrazole-based ligands used in homogeneous catalysis and material science.
• Functional Material Research: Employed in the synthesis of organic electronic materials and liquid crystals, where its structural motifs can tune electronic properties.
• Custom Chemical Synthesis: A valuable building block for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for client projects.

Basic Information

Product Name	5-(Chloromethyl)-1-Methyl-3-(Trifluoromethyl)-1H-Pyrazole
CAS No.	184358-63-2
Molecular Formula	C6H6ClF3N2
Molecular Weight	198.57 g/mol
Synonyms	1-Methyl-3-(trifluoromethyl)-5-(chloromethyl)-1H-pyrazole; 5-(Chloromethyl)-1-methyl-3-(trifluoromethyl)pyrazole; 1H-Pyrazole, 5-(chloromethyl)-1-methyl-3-(trifluoromethyl)-; 184358-63-2; 5-Chloromethyl-1-methyl-3-trifluoromethylpyrazole
EINECS	Contact for details

Quality Control

Every batch of our 5-(Chloromethyl)-1-Methyl-3-(Trifluoromethyl)-1H-Pyrazole is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is stable under inert atmosphere but should be kept away from strong acids and strong oxidizing agents. Keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.