Description

Benzyl Spiro[Indole-3,4'-Piperidine]-1'-Carboxylate is a high-value, advanced pharmaceutical intermediate featuring a complex spirocyclic molecular architecture. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates targeting various receptors.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns.
• CNS Drug Development: Employed in the research of novel therapeutics for neurological and psychiatric disorders due to its spiro[indole-3,4'-piperidine] core, a privileged structure in neuropharmacology.
• Oncology Research: Serves as a building block for synthesizing molecules being investigated for anti-cancer properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for studies in organic synthesis methodology and bioactivity exploration.

Basic Information

Product Name	Benzyl Spiro[Indole-3,4'-Piperidine]-1'-Carboxylate
CAS No.	184289-85-8
Molecular Formula	C20H20N2O2
Molecular Weight	320.39 g/mol
Synonyms	1'-Benzyloxycarbonylspiro[indole-3,4'-piperidine]; Benzyl 1'H-spiro[indole-3,4'-piperidine]-1'-carboxylate; Spiro[indole-3,4'-piperidine]-1'-carboxylic acid benzyl ester; 1'-Cbz-Spiro[indole-3,4'-piperidine]; Cbz-Spiroindolepiperidine; 1'-(Benzyloxycarbonyl)spiro[indole-3,4'-piperidine]; (1'Benzyloxycarbonyl)spiro[indoline-3,4'-piperidine]
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. Each batch is characterized and controlled using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing key parameters such as assay (HPLC), related substances, and residual solvents. We adhere to cGMP principles where applicable to support our clients' regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.