Description

Methyl 2-Amino-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxylate CAS NO 184174-81-0 is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused ring structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex heterocyclic molecules. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting neurological and oncological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Heterocyclic Compound Synthesis: Used in the construction of complex polycyclic frameworks common in modern bioactive molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of proprietary compounds.
• Academic Research: Utilized in university and institutional labs for studying synthetic methodologies and new chemical entities.

Basic Information

Item	Details
Product Name	Methyl 2-Amino-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxylate
CAS No.	184174-81-0
Molecular Formula	C11H15NO2S
Molecular Weight	225.31 g/mol
Synonyms	Methyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate (7-membered ring); 2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid methyl ester; Methyl 2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-3-carboxylate; 3-Carbomethoxy-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene; 2-Amino-3-methoxycarbonyl-4,5,6,7-tetrahydrobenzo[b]thiophene; 184174-81-0; Cycloheptathiophene carboxylate derivative
EINECS	Contact for details

Quality Control

Our Methyl 2-Amino-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure compliance with stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.