Description

2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylic Acid Methyl Ester is a high-value, fused-ring heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by research and development chemists and process development teams within the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a core structure for developing new pesticides and herbicides with unique modes of action.
• Material Science: Used in the research of organic semiconductors and conductive polymers due to its electron-rich thiophene core.
• Chemical Biology: Employed as a scaffold for designing molecular probes and enzyme inhibitors to study biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fused bicyclic systems with both amino and ester functionalities.

Basic Information

Product Name	2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylic Acid Methyl Ester
CAS No.	184174-80-9
Molecular Formula	C9H11NO2S
Molecular Weight	197.26 g/mol
Synonyms	Methyl 2-amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; Methyl 2-amino-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate; 2-Amino-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid methyl ester; 3-Carbomethoxy-2-amino-4,5,6,7-tetrahydrobenzo[b]thiophene; 2-Amino-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our 2-Amino-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxylic Acid Methyl Ester is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.