Description

tert-Butyl 4-(6-Fluoro-1,2-Dihydro-2-Oxobenzo[D]Imidazol-3-Yl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. Its core value lies in its role as a critical building block for the synthesis of complex bioactive molecules, particularly in medicinal chemistry. This compound is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization processes.
• Protease Inhibitor Development: Serves as a core scaffold for molecules designed to inhibit specific enzyme classes.
• Kinase Inhibitor Synthesis: Integral to the construction of heterocyclic compounds targeting kinase proteins for cancer therapy.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.
• Biochemical Tool Compound: Utilized in academic and industrial research to probe biological mechanisms and validate drug targets.

Basic Information

Product Name	tert-Butyl 4-(6-Fluoro-1,2-Dihydro-2-Oxobenzo[D]Imidazol-3-Yl)Piperidine-1-Carboxylate
CAS No.	182365-86-2
Molecular Formula	C17H20FN3O3
Molecular Weight	333.36 g/mol
Synonyms	1-Boc-4-(6-Fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(6-fluoro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine; tert-Butyl 4-(6-fluoro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)piperidine-1-carboxylate; 4-(6-Fluoro-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1-carboxylic acid tert-butyl ester; 182365-86-2; 1-Piperidinecarboxylic acid, 4-(6-fluoro-2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(6-Fluoro-1,2-Dihydro-2-Oxobenzo[D]Imidazol-3-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.