Description

tert-Butyl 5-Bromoindole-1-Carboxylate is a high-purity, versatile indole derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a protected indole nitrogen and a reactive bromine substituent, enabling precise molecular construction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in oncology and CNS (Central Nervous System) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that require functionalized indole scaffolds.
• Material Science: Serves as a precursor for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Academic & R&D: A valuable reagent for methodological studies in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and indole chemistry.
• Peptidomimetics & Bioconjugation: The tert-butyloxycarbonyl (Boc) protecting group makes it suitable for constructing complex molecules in medicinal chemistry.

Basic Information

Product Name	tert-Butyl 5-Bromoindole-1-Carboxylate
CAS No.	182344-70-3
Molecular Formula	C13H14BrNO2
Molecular Weight	296.16 g/mol
Synonyms	1-Boc-5-Bromoindole; 5-Bromo-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester; 5-Bromoindole-1-carboxylic Acid tert-Butyl Ester; tert-Butyl 5-bromo-1H-indole-1-carboxylate; 1-(tert-Butoxycarbonyl)-5-bromoindole; 5-Bromo-1-(tert-butoxycarbonyl)indole; 5-Bromoindole, N-Boc protected; Boc-5-Br-indole
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Bromoindole-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.