Description

3-Formyl-4-Hydroxyphenylboronic Acid is a multifunctional boronic acid derivative that serves as a key building block in modern synthetic chemistry. Its unique structure, combining a formyl group, a phenolic hydroxyl, and a boronic acid moiety, makes it a versatile intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for Suzuki-Miyaura cross-coupling reactions and other advanced synthetic applications.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting inflammation, cancer, and central nervous system disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators through cross-coupling chemistry.
• Material Science & OLED Development: Serves as a building block for creating advanced organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers in organic light-emitting diodes (OLEDs).
• Sensor & Diagnostic Reagent: Utilized in the fabrication of chemical sensors and diagnostic assays that leverage the selective binding properties of boronic acids to diols and sugars.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic synthesis and catalysis research within university and corporate R&D settings.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated ligands for transition metal catalysts used in asymmetric synthesis.

Basic Information

Product Name	3-Formyl-4-Hydroxyphenylboronic Acid
CAS No.	182344-24-7
Molecular Formula	C7H7BO4
Molecular Weight	165.94 g/mol
Synonyms	4-Hydroxy-3-formylbenzeneboronic Acid; (4-Hydroxy-3-formylphenyl)boronic Acid; 3-Carboxy-4-hydroxybenzeneboronic Acid (tautomeric form); 4-Hydroxy-3-carboxybenzeneboronic Acid; 3-Formyl-4-hydroxybenzeneboronic Acid; 4-Hydroxybenzaldehyde-3-boronic Acid; 3-Formyl-4-hydroxy-phenylboronic acid; 3-Formyl-4-hydroxybenzeneboronic acid pinacol ester (common protected form)
EINECS	Contact for details

Quality Control

Our 3-Formyl-4-Hydroxyphenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.