Description

Corey 21 CAS NO 182201-62-3 is a high-purity, advanced pharmaceutical intermediate, also known as (R)-4-Benzyl-3-propionyl-2-oxazolidinone. This compound is a crucial chiral auxiliary and building block in asymmetric synthesis, enabling the production of enantiomerically pure active pharmaceutical ingredients (APIs). It is essential for research and manufacturing chemists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for complex organic synthesis.

Application

• Asymmetric Synthesis: As a versatile chiral auxiliary for the stereoselective alkylation, aldol, and Diels-Alder reactions.
• Pharmaceutical Intermediates: Key building block in the synthesis of complex drug molecules, particularly those requiring specific stereochemistry.
• Agrochemical Development: Used in the research and production of chiral pesticides and herbicides.
• Academic & Industrial R&D: A standard reagent in laboratories for methodological development in organic chemistry.
• Fine Chemical Production: For the manufacture of specialty chemicals where high enantiomeric purity is critical.

Basic Information

Product Name	Corey 21 CAS NO 182201-62-3
CAS No.	182201-62-3
Molecular Formula	C₁₃H₁₅NO₃
Molecular Weight	233.26 g/mol
Synonyms	(R)-4-Benzyl-3-propionyl-2-oxazolidinone; (R)-(-)-4-Benzyl-3-propionyl-2-oxazolidinone; (R)-4-Benzyl-3-propionyloxazolidin-2-one; Corey's (R)-4-Benzyl-3-propionyl-2-oxazolidinone; (R)-N-Propionyl-4-benzyl-2-oxazolidinone; (R)-3-Propionyl-4-benzyloxazolidin-2-one; (R)-PBX; Corey Chiral Auxiliary 21
EINECS	Contact for details

Quality Control

Our Corey 21 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Specified range
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.