Description

Oxazole, 2,2'-(1-Methylethylidene)Bis[4,5-Dihydro-4-Methyl-, (4S,4'S)- is a high-purity, chiral bis-oxazole compound with a defined stereochemistry, serving as a sophisticated building block in advanced organic synthesis. Its value lies in its rigid, bidentate structure, which is crucial for constructing complex molecular architectures, particularly in the development of chiral catalysts and ligands. This product is essential for research and production in the pharmaceutical and fine chemical industries, where precise stereochemical control is paramount for creating active pharmaceutical ingredients (APIs) and specialty materials.

Application

• Chiral Ligand Synthesis: A key precursor for the preparation of novel, enantioselective ligands used in asymmetric catalysis.
• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of complex, stereochemically-defined drug candidates.
• Catalyst Development: Used in research to develop and optimize new metal-organic frameworks (MOFs) and homogeneous catalysts.
• Fine Chemical Production: Employed in the manufacture of high-value specialty chemicals requiring specific chiral environments.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate labs exploring new synthetic methodologies.
• Material Science Research: Investigated for potential use in creating chiral polymers or advanced functional materials.

Basic Information

Product Name	Oxazole, 2,2'-(1-Methylethylidene)Bis[4,5-Dihydro-4-Methyl-, (4S,4'S)-
CAS No.	181708-51-0
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	(4S,4'S)-2,2'-(2-Methylpropane-2,2-diyl)bis(4-methyl-4,5-dihydrooxazole); (4S,4'S)-2,2'-Isopropylidenebis(4-methyl-4,5-dihydrooxazole); (S,S)-2,2'-Isopropylidenebis(4-methyl-2-oxazoline); (S,S)-Bis(4-methyl-4,5-dihydrooxazol-2-yl)methane Derivative; Chiral Bis(oxazoline) Ligand Precursor; (S,S)-tert-Butyl-bis(4-methyl-4,5-dihydrooxazole); Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of Oxazole, 2,2'-(1-Methylethylidene)Bis[4,5-Dihydro-4-Methyl-, (4S,4'S)- is produced under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and enantiomeric excess meet stringent specifications. Our quality assurance protocols are designed to support cGMP-compliant applications where required. A comprehensive Certificate of Analysis (COA) detailing chiral purity (HPLC), assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to preserve stability and chiral integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.