Description

6-(Trifluoromethyl)Indoline is a high-value fluorinated heterocyclic building block essential for advanced organic synthesis. This compound matters for its unique trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. It is primarily needed by pharmaceutical, agrochemical, and material science research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the CF3 group improves biological activity.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials requiring fluorinated components.
• Chemical Research: Employed as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorine Chemistry: Acts as a model compound for studying the introduction and reactivity of the trifluoromethyl group in complex heterocyclic systems.

Basic Information

Product Name	6-(Trifluoromethyl)Indoline
CAS No.	181513-29-1
Molecular Formula	C9H8F3N
Molecular Weight	187.16 g/mol
Synonyms	6-(Trifluoromethyl)-2,3-dihydro-1H-indole; 6-(Trifluoromethyl)indoline; 1H-Indole, 2,3-dihydro-6-(trifluoromethyl)-; 2,3-Dihydro-6-(trifluoromethyl)-1H-indole; Indoline, 6-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Indoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.