Description

5-(Bromomethyl)-4-Methyl-2-Phenyl-1,3-Thiazole is a high-value brominated thiazole derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its core value lies in its reactive bromomethyl group, which facilitates efficient alkylation and functionalization reactions, enabling the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries, particularly for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those containing thiazole pharmacophores with potential biological activity.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiazole ring's bioactivity.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, or organic electronic materials due to its aromatic and heterocyclic structure.
• Chemical Biology Probes: Utilized in the creation of molecular probes and tags for studying biological processes, where the bromine acts as a handle for further conjugation.
• Cross-Coupling Reactions: Acts as a substrate in various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to form carbon-carbon bonds.
• Ligand and Catalyst Development: Intermediate for synthesizing novel nitrogen-sulfur containing ligands for metal catalysis.

Basic Information

Product Name	5-(Bromomethyl)-4-Methyl-2-Phenyl-1,3-Thiazole
CAS No.	181424-15-7
Molecular Formula	C11H10BrNS
Molecular Weight	268.17 g/mol
Synonyms	4-Methyl-2-phenyl-5-(bromomethyl)thiazole; 2-Phenyl-4-methyl-5-(bromomethyl)thiazole; 5-Bromomethyl-4-methyl-2-phenylthiazole; 1,3-Thiazole, 5-(bromomethyl)-4-methyl-2-phenyl-; 181424-15-7; 4-Methyl-2-phenyl-5-thiazolylmethyl bromide
EINECS	Contact for details

Quality Control

Our 5-(Bromomethyl)-4-Methyl-2-Phenyl-1,3-Thiazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.