Description

Ethyl 3-Amino-4-Methylbenzo[B]Thiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate with a distinct benzo[b]thiophene core structure. This compound is valued for its role as a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new molecular entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for biological activity.
• Organic Synthesis Building Block: Serves as a versatile starting material for constructing complex polycyclic structures in academic and industrial research laboratories.
• Material Science Precursor: Potential use in the synthesis of organic semiconductors, dyes, and photoactive materials due to its conjugated system.

Basic Information

Product Name	Ethyl 3-Amino-4-Methylbenzo[B]Thiophene-2-Carboxylate
CAS No.	181284-94-6
Molecular Formula	C12H13NO2S
Molecular Weight	235.30 g/mol
Synonyms	Ethyl 3-Amino-4-Methyl-1-Benzothiophene-2-Carboxylate; 3-Amino-4-methylbenzo[b]thiophene-2-carboxylic acid ethyl ester; 2-Carbethoxy-3-amino-4-methylbenzo[b]thiophene; 4-Methyl-3-aminobenzo[b]thiophene-2-carboxylic acid ethyl ester; Ethyl 3-amino-4-methylbenzothiophene-2-carboxylate; AMBTC ethyl ester; 181284-94-6
EINECS	Contact for details

Quality Control

Our Ethyl 3-Amino-4-Methylbenzo[B]Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.