Description

Methyl 3-Amino-7-Chlorobenzo[B]Thiophene-2-Carboxylate is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. Its core value lies in its functionalized benzothiophene scaffold, which serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating new molecular entities with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for creating organic semiconductors, dyes, and photostable polymers.
• Chemical Biology: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.

Basic Information

Product Name	Methyl 3-Amino-7-Chlorobenzo[B]Thiophene-2-Carboxylate
CAS No.	181283-33-0
Molecular Formula	C10H8ClNO2S
Molecular Weight	241.69 g/mol
Synonyms	Methyl 3-Amino-7-Chlorobenzo[B]Thiophene-2-Carboxylate; 3-Amino-7-chlorobenzo[b]thiophene-2-carboxylic acid methyl ester; 7-Chloro-3-aminobenzo[b]thiophene-2-carboxylic acid methyl ester; Methyl 3-amino-7-chloro-1-benzothiophene-2-carboxylate; 2-Carbomethoxy-3-amino-7-chlorobenzo[b]thiophene; 181283-33-0; Methyl 7-chloro-3-aminobenzo[b]thiophene-2-carboxylate
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-7-Chlorobenzo[B]Thiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.