Description

Methyl 3-Amino-7-Cyano-1-Benzothiophene-2-Carboxylate is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is valued for its unique molecular scaffold, which combines an amino group, a nitrile, and an ester moiety on a benzothiophene core, enabling diverse chemical transformations. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, dyes, and photoactive materials due to its conjugated benzothiophene system.
• Chemical Synthesis: Utilized in academic and industrial R&D for constructing complex heterocyclic libraries via reactions at its amino, cyano, and ester functional groups.
• Ligand and Catalyst Development: The amino and nitrile groups make it a useful precursor for creating specialized ligands in coordination chemistry and catalysis.

Basic Information

Product Name	Methyl 3-Amino-7-Cyano-1-Benzothiophene-2-Carboxylate
CAS No.	181283-29-4
Molecular Formula	C11H8N2O2S
Molecular Weight	232.26 g/mol
Synonyms	Methyl 3-amino-7-cyano-1-benzothiophene-2-carboxylate; 3-Amino-7-cyano-1-benzothiophene-2-carboxylic acid methyl ester; 2-Carbomethoxy-3-amino-7-cyanobenzothiophene; Methyl 3-amino-7-cyanobenzo[b]thiophene-2-carboxylate; 7-Cyano-3-aminobenzothiophene-2-methyl carboxylate; 181283-29-4; Benzo[b]thiophene-2-carboxylic acid, 3-amino-7-cyano-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-7-Cyano-1-Benzothiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality parameters. Our commitment to cGMP and ISO standards ensures reliable supply for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere for prolonged stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.