Description

Methyl 3-(Tosyloxy)Thiophene-2-Carboxylate is a high-value, multi-functional chemical intermediate, primarily recognized for its role as a versatile building block in advanced organic synthesis. Its core value lies in enabling the efficient construction of complex heterocyclic scaffolds, which are pivotal in the development of novel active compounds. This product is essential for research and development chemists and process engineers in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing complex thiophene or fused heterocyclic ring systems.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, leveraging the thiophene moiety for biological activity.
• Material Science Research: Serves as a monomer or building block for the development of conductive polymers, organic semiconductors, and advanced organic electronic materials.
• Organic Synthesis Building Block: Facilitates cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitutions due to the reactive tosyloxy group, enabling diverse molecular diversification.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for catalysis or as a core structure in metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Used in the synthesis of specialized dyes and pigments where the thiophene unit contributes to color and stability properties.

Basic Information

Product Name	Methyl 3-(Tosyloxy)Thiophene-2-Carboxylate
CAS No.	181226-89-1
Molecular Formula	C13H12O5S2
Molecular Weight	312.36 g/mol
Synonyms	Methyl 3-[(4-methylphenyl)sulfonyl]oxy-2-thiophenecarboxylate; 3-[(Tosyl)oxy]thiophene-2-carboxylic acid methyl ester; Methyl 3-(p-toluenesulfonyloxy)thiophene-2-carboxylate; 2-Thiophenecarboxylic acid, 3-[(4-methylphenyl)sulfonyl]oxy-, methyl ester; Methyl 3-(tosyloxy)-2-thiophenecarboxylate; MTTC; 181226-89-1
EINECS	Contact for details

Quality Control

Our Methyl 3-(Tosyloxy)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.