Description

2-Thiophenecarboxylicacid,3-Ethoxy-,Ethylester(9Ci) CAS NO 181063-54-7 is a specialized thiophene derivative ester, a high-purity organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where the thiophene moiety is valued for its unique electronic and structural properties. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the thiophene ring can enhance biological activity and selectivity.
• Material Science Research: Acts as a monomer or precursor in the development of organic semiconductors, conductive polymers, and other functional materials due to its conjugated system.
• Organic Synthesis & Catalysis: Employed as a versatile reagent in cross-coupling reactions, such as Suzuki or Stille couplings, to introduce functionalized thiophene units into more complex structures.
• Ligand Preparation: Can be utilized to synthesize novel ligands for coordination chemistry and catalysis, leveraging the sulfur atom for metal binding.
• Fine Chemical Production: Functions as an intermediate in the manufacture of dyes, flavors, and fragrances that require specific heterocyclic frameworks.

Basic Information

Product Name	2-Thiophenecarboxylicacid,3-Ethoxy-,Ethylester(9Ci)
CAS No.	181063-54-7
Molecular Formula	C9H12O3S
Molecular Weight	200.26 g/mol
Synonyms	Ethyl 3-ethoxy-2-thiophenecarboxylate; 3-Ethoxy-2-thiophenecarboxylic Acid Ethyl Ester; 2-Thiophenecarboxylic acid, 3-ethoxy-, ethyl ester; Ethyl 3-ethoxythiophene-2-carboxylate; Thiophene-2-carboxylic acid, 3-ethoxy-, ethyl ester; 3-Ethoxythiophene-2-carboxylic acid ethyl ester; 181063-54-7; Ethyl 3-ethoxy-2-thiophenecarboxylate (9CI)
EINECS	Contact for details

Quality Control

Our production of 2-Thiophenecarboxylicacid,3-Ethoxy-,Ethylester(9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.