Description

1H-Pyrrole-2,5-Dione, 1-(5-Hydroxypentyl) CAS NO 180608-78-0 is a functionalized maleimide derivative characterized by its hydroxypentyl side chain. This compound serves as a versatile chemical building block and cross-linking agent, enabling the synthesis of advanced polymers and functional materials. It is primarily utilized by R&D chemists and process engineers in the pharmaceutical intermediates, specialty polymer, and bioconjugation sectors.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs) and drug candidates.
• Polymer Modification: Used as a reactive monomer or cross-linker to introduce functional groups into polyimides, polyamides, and other high-performance polymers.
• Bioconjugation & Protein Labeling: The maleimide group selectively reacts with thiols (-SH) in peptides, proteins, and antibodies for labeling and immobilization applications.
• Material Science: Building block for creating functional coatings, adhesives, and composites with tailored thermal or mechanical properties.
• Research & Development: Valuable reagent in organic synthesis for constructing heterocyclic compounds and complex molecular architectures.
• Surface Functionalization: Used to modify the surface properties of nanoparticles, silica, or other substrates for specific interactions.

Basic Information

Product Name	1H-Pyrrole-2,5-Dione, 1-(5-Hydroxypentyl)
CAS No.	180608-78-0
Molecular Formula	C9H13NO3
Molecular Weight	183.20 g/mol
Synonyms	1-(5-Hydroxypentyl)-1H-pyrrole-2,5-dione; N-(5-Hydroxypentyl)maleimide; 5-Hydroxypentylmaleimide; Maleimide, N-(5-hydroxypentyl)-; 1-(5-Hydroxyamyl)-1H-pyrrole-2,5-dione; N-Hydroxypentylmaleimide; 180608-78-0; N-(5-Hydroxypentyl)maleimide
EINECS	Contact for details

Quality Control

Our 1-(5-Hydroxypentyl)-1H-pyrrole-2,5-dione is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.