Description

6-Fluoro-3-(Piperidin-4-Yl)-1H-Indole Hydrochloride is a high-purity, pharmaceutically relevant indole derivative supplied as a hydrochloride salt. This compound serves as a critical advanced pharmaceutical intermediate for the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and contract manufacturing organizations (CMOs) engaged in drug discovery programs targeting central nervous system (CNS) disorders and oncology.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent and selective drug candidates, particularly for neurological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize pharmacokinetic and pharmacodynamic properties of lead compounds.
• API Development: Serves as a precursor in the development of Active Pharmaceutical Ingredients (APIs) for preclinical and clinical studies.
• CNS Drug Discovery: Employed in the research of novel treatments for conditions such as depression, anxiety, schizophrenia, and neurodegenerative diseases.
• Kinase Inhibitor Synthesis: A valuable scaffold for the development of protein kinase inhibitors with potential applications in oncology.
• Chemical Biology Probes: Used to create tool compounds for studying biological pathways and target validation.

Basic Information

Product Name	6-Fluoro-3-(Piperidin-4-Yl)-1H-Indole Hydrochloride
CAS No.	180411-84-1
Molecular Formula	C13H15FN2•HCl
Molecular Weight	254.73 g/mol
Synonyms	6-Fluoro-3-(4-piperidinyl)-1H-indole hydrochloride; 3-(Piperidin-4-yl)-6-fluoro-1H-indole hydrochloride; 1H-Indole, 6-fluoro-3-(4-piperidinyl)-, hydrochloride; 6-Fluoro-3-piperidin-4-yl-1H-indole HCl; 6-Fluoro-3-(4-piperidyl)indole hydrochloride; 180411-84-1; 6-Fluoro-3-(piperidin-4-yl)indole hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3-(Piperidin-4-Yl)-1H-Indole Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development with custom synthesis and scale-up services under cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.