Description

2-Piperidino-1,3-Thiazole-5-Carboxylic Acid is a high-value heterocyclic building block and synthetic intermediate of significant interest in advanced organic chemistry. Its core value lies in its unique molecular architecture, which combines a piperidine moiety with a thiazole-carboxylic acid scaffold, enabling the synthesis of complex molecules with targeted biological or material properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting neurological or metabolic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or insecticides that leverage its heterocyclic core for bioactivity.
• Ligand & Catalyst Development: Serves as a building block for creating complex ligands used in asymmetric catalysis or metal-organic frameworks (MOFs).
• Material Science: Investigated for the synthesis of advanced polymers or organic electronic materials due to its conjugated system and functional groups.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function or cellular processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the pharmaceutical and biotechnology industries.

Basic Information

Product Name	2-Piperidino-1,3-Thiazole-5-Carboxylic Acid
CAS No.	180403-13-8
Molecular Formula	C9H12N2O2S
Molecular Weight	212.27 g/mol
Synonyms	2-(Piperidin-1-yl)-1,3-thiazole-5-carboxylic acid; 2-Piperidin-1-yl-1,3-thiazole-5-carboxylic acid; 5-Thiazolecarboxylic acid, 2-(1-piperidinyl)-; 2-(1-Piperidinyl)-5-thiazolecarboxylic acid; Piperidin-1-yl-thiazole-5-carboxylic acid; 180403-13-8; 2-Piperidinothiazole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Piperidino-1,3-Thiazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay (HPLC), related substances, residual solvents, and physical characteristics. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.