Description

4-Bromobutyl 2-Bromoacetate is a specialized bifunctional bromoalkyl ester of significant interest in advanced organic synthesis. This compound serves as a versatile and reactive building block, enabling the introduction of both bromoalkyl and bromoacetyl functionalities in a single step. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures, including active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring bromoalkyl or bromoacetyl side chains for biological activity or further derivatization.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where its reactive bromine atoms facilitate the construction of specific bioactive cores.
• Polymer & Material Science: Acts as a functional monomer or cross-linking agent in the production of specialty polymers, coatings, and resins with tailored properties.
• Organic Synthesis Building Block: Employed in alkylation and esterification reactions to introduce functional handles for subsequent coupling (e.g., Suzuki, Heck) or nucleophilic substitution reactions.
• Ligand & Catalyst Development: Useful for synthesizing novel ligands or organocatalysts in asymmetric synthesis and transition metal catalysis.
• Bioconjugation & Probe Synthesis: Facilitates the creation of chemical probes, tags, or linkers for bioconjugation applications in diagnostic and biochemical research.

Basic Information

Product Name	4-Bromobutyl 2-Bromoacetate
CAS No.	180386-87-2
Molecular Formula	C6H10Br2O2
Molecular Weight	273.95 g/mol
Synonyms	2-Bromoacetic Acid 4-Bromobutyl Ester; 4-Bromobutyl Bromoacetate; 1,4-Dibromobutyl Acetate; Butane-1,4-diyl bis(bromoacetate) (common misnomer); Bromoacetic Acid 4-Bromobutyl Ester; 4-Bromobutanol Bromoacetate; NSC 405124; 180386-87-2
EINECS	Contact for details

Quality Control

Our 4-Bromobutyl 2-Bromoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents. The container should be kept tightly sealed when not in use to minimize moisture absorption and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.