Description

Carbamic Acid, [4-(1,1-Difluoro-2-Hydroxyethyl)-2-Thiazolyl]-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organofluorine compound featuring a carbamate-protected thiazole core. This molecule matters as a key synthetic intermediate, offering a protected amine and a reactive hydroxyl group for constructing complex pharmacologically active molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• As a key building block in the synthesis of novel pharmaceutical candidates, particularly those targeting infectious diseases or metabolic disorders.
• As a versatile chemical intermediate for the development of advanced agrochemicals, such as herbicides or fungicides with improved efficacy.
• In medicinal chemistry research for structure-activity relationship (SAR) studies, leveraging its modifiable thiazole and carbamate functionalities.
• For the preparation of custom fluorinated compounds in academic and industrial research settings, exploring the unique properties imparted by the difluoro moiety.
• As a starting material in process chemistry for scaling up the production of target active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Carbamic Acid, [4-(1,1-Difluoro-2-Hydroxyethyl)-2-Thiazolyl]-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	180207-42-5
Molecular Formula	C10H15F2N2O3S
Molecular Weight	281.30 g/mol
Synonyms	tert-Butyl [4-(1,1-difluoro-2-hydroxyethyl)-1,3-thiazol-2-yl]carbamate; 2-[[(tert-Butoxy)carbonyl]amino]-4-(1,1-difluoro-2-hydroxyethyl)thiazole; 4-(1,1-Difluoro-2-hydroxyethyl)-2-thiazolylcarbamic acid 1,1-dimethylethyl ester; N-Boc-4-(1,1-difluoro-2-hydroxyethyl)thiazol-2-amine; Boc-4-(1,1-difluoro-2-hydroxyethyl)thiazol-2-ylamine; CAS 180207-42-5
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [4-(1,1-Difluoro-2-Hydroxyethyl)-2-Thiazolyl]-, 1,1-Dimethylethyl Ester (9Ci) is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), related substances, and other critical parameters is provided with each shipment to support your R&D and quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its chemical nature, it should be kept separate from strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.