Description

6-Fluoro-3-(1,2,3,6-Tetrahydro-Pyridin-4-Yl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its unique indole and tetrahydro-pyridine fused-ring structure. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of central nervous system (CNS) and neurological disorder therapeutics. Our supply ensures consistent quality and reliable availability for global R&D and production-scale projects.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates targeting serotonin and dopamine receptors.
• Neurological Research: Used in medicinal chemistry programs for developing novel treatments for conditions like depression, anxiety, and schizophrenia.
• Chemical Biology: Serves as a scaffold or probe in studying protein-ligand interactions and receptor binding assays.
• Process Development: Employed in route scouting and optimization for the scalable manufacturing of target APIs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical innovation.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic and pharmacological studies.

Basic Information

Product Name	6-Fluoro-3-(1,2,3,6-Tetrahydro-Pyridin-4-Yl)-1H-Indole
CAS No.	180161-14-2
Molecular Formula	C13H13FN2
Molecular Weight	216.26 g/mol
Synonyms	6-Fluoro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole; 6-Fluoro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole; 6-Fluoro-3-(1,2,3,6-tetrahydro-4-pyridyl)indole; 4-(6-Fluoro-1H-indol-3-yl)-1,2,3,6-tetrahydropyridine; 180161-14-2; 6-Fluoro-3-(1,2,3,6-tetrahydro-pyridin-4-yl)-indole
EINECS	Contact for details

Quality Control

Our 6-Fluoro-3-(1,2,3,6-Tetrahydro-Pyridin-4-Yl)-1H-Indole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.